The Grizzard Center for Cherokee Studies is located in the two-story brick home directly adjacent to the museum. It houses the museum’s research library, archival and artifacts collections, and provides a learning space for those researching Cherokee history. The Center can be reserved for research appointments, meetings, and small events.

The Chieftains Museum/Major Ridge Home Digital Collections is the museum’s digital repository. It provides electronic access to images, manuscripts, and artifacts in the museum's collections which relate to its life as a private home and historic site of Cherokee history and culture.